What Should You Not Take With Metformin: Proper/Best Way To Take & Time


Many people who need to take Metformin may wonder if they can drink coffee. The answer is yes, as long as there are no adverse effects or drug interactions So, what should you not take with metaformin tablets?

To consider is that coffee can increase blood sugar levels, leading to unwanted side effects. Also, combinations with Metformin may cause a more substantial impact than intended. 

As a result, some individuals may choose not to drink coffee while taking Metformin and explore other options such as caffeine-free tea. 

Remember that this will depend on the individual because everyone has different tolerances, so consult your doctor before changing your medication routine.

So, What is the proper way to take metformin? What happens if you take metformin without food? What time is best to take metformin? To take metformin, you can take it with or without food. 

The general practice is to take the medication with breakfast, but if you must take it at another time of the day, avoid taking it after dinner. Read more here …

What should you not take with metformin:What Is Metformin?

Metformin is a drug prescribed to patients with diabetes to help manage blood sugar levels.

What are the benefits of taking metformin?

Metformin works by reducing glucose production by the liver and decreasing glucose absorption in the intestines. It also increases sensitivity to insulin, a hormone that helps convert glucose into energy. 

As a result, it allows glucose and other nutrients to travel more efficiently throughout your body.

Metformin’s most significant advantage is that it doesn’t cause weight gain like other medications for diabetes do.

Metformin has been around since the 1950s. Metformin is available in generic form and is reasonably priced.

What Does Metformin Do?

Metformin works by regulating the levels of blood sugar in your body. It is done in a few different ways, including:

  • Reducing liver glucose production 
  • Reducing the absorption of glucose from food into your bloodstream 
  • Increasing sensitivity to insulin, a hormone that helps convert glucose into energy. It allows glucose and other nutrients to travel more efficiently throughout your body.

What Are The Side Effects Of Metformin?

Metformin may cause side effects, but many are very mild and disappear without treatment. Some of the most common metformin side effects include bloating, gas, stomach pain, diarrhoea, nausea (feeling sick to your stomach), constipation, headache, and fatigue. Metformin may also make your urine more orange or dark yellow. 

What are the worst side effects of metformin?
Metformin is available under many brand names, including Glucophage, Merck, and Novo-Met. Read on to know What should you not take with metformin as well!

Can People Take Both Caffeine And Metformin?

The body breaks down caffeine to be eliminated. Metformin can slow down the rate at which the body breaks down coffee.

Therefore, caffeine's and adverse effects may be enhanced when Metformin is used with caffeine. However, some people drink coffee while taking Metformin and don't have any side effects.

Other doctors recommend drinking only one cup of coffee a day while taking Metformin.

How Often Should I Take Metformin? 

Metformin can be taken anytime, but most doctors suggest taking it once or twice a day, depending on how well your diabetes is controlled.

The exact amount you take also depends on your individual needs. Follow the instructions on the packaging and ask your doctor or pharmacist if you have any questions.

Coffee And Metformin – Is It Safe?

I’m glad you asked. Coffee and Metformin are both safe to take together. The FDA limits the amount of caffeine in a certain amount of products.

What should I avoid while taking metformin?

They also restrict other ingredients in some products that have been shown to have harmful effects as well, so make sure you know how much coffee you are drinking per cup or can before consuming it. 

Many medical studies have been done on Metformin and coffee to ensure they are safe together.

What is the best time of day to take metformin?

Metformin is usually taken once daily with the evening meal. Some individuals may take their doses with breakfast or lunch.

Why should metformin be taken at night?

Metformin is usually taken at night to help reduce the possibility of adverse effects like nausea, vomiting, and diarrhea.

What happens if I take metformin on an empty stomach?

Metformin should be taken with a meal or snack to help the body manage the side effects.

Does metformin lower blood sugar immediately?

Metformin can take a few weeks to help lower blood sugar, although some individuals may be more sensitive to changes.

Does anything interfere with metformin?

Yes! People who take metformin should avoid anything that slows down the body’s ability to handle medicines, like grapefruit juice, cimetidine (Tagamet), diclofenac (Voltaren), ibuprofen (Motrin) and many others.

Can I take vitamin D with metformin?

Yes, there is evidence that suggests low vitamin D levels in diabetics are associated with an earlier onset of diabetic complications. It is prudent to maintain a serum 25-hydroxy vitamin D level of at least 32 ng/mL.
Also, vitamin D has been shown to slow down the progression of kidney disease by improving the functioning of the kidneys.
Therefore, it is recommended that all patients taking metformin should take a daily dose of at least 1000 units of vitamin D3.

What pain reliever can I take with metformin?

You may take painkillers as required with your metformin. However, do not take non-steroidal anti-inflammatory drugs (NSAIDS) such as ibuprofen (Advil), naproxen (Aleve) or aspirin while you are being treated with metformin. This is because NSAIDS may increase the risk of stomach bleeding when taken in combination with metformin.

What vitamins does metformin interact with?

Metformin affects vitamin B12 and folic acid levels so supplementing is recommended.


1. What should you not take with metformin at all?

Metformin (brand name Glucophage) is a biguanide, a type of drug used to treat type 2 diabetes.

The list of things that should not be taken at the same time with metformin is long and includes anything that slows blood clotting, such as aspirin, non-steroidal anti-inflammatory drugs (NSAIDs), warfarin (Coumadin), diclofenac (Voltaren), ibuprofen (Motrin) and many others.

2. What happens if you take metformin without food?

Metformin can be taken with or without food. However, not eating anything before taking your metformin may help you to absorb the medicine.

3. What time is best to take metformin?

Take your metformin at regular intervals throughout the day. The dose can vary depending on your medical condition and response to treatment. The best time is 10-15 minutes before meal!

4. What is the proper way to take metformin?

Metformin should be taken with meals to assist lessen the possibility of stomach or intestinal side effects during the first few weeks of treatment.

With a full glass of water, swallow the pill or extended-release tablet whole. It should not be crushed, broken, or chewed.

Conclusion on What should you not take with metformin

It’s a good idea to be careful when drinking coffee with Metformin. Metformin and coffee alone are generally safe to consume together. 

However, Metformin may interact with certain drugs, so discuss the addition of coffee or any other foods or beverages you drink while taking this medication with your doctor. 

So you must know what is the proper way to take metformin and what time is best to take metformin! You must also know what happens if you take metformin without food, or what happens if you take metformin with some other foods in the same time.

I hope this article answered your questions about how coffee and Metformin interact. If you have any other questions, please leave a comment below.

Similar Posts

Leave a Reply

Your email address will not be published. Required fields are marked *